Lallemand Pharma


Rhino-sinusitis (or sinusitis) is an inflammation or infection of the lining of the sinus cavities, triggered by a viral, bacterial or fungal infection. It is one of the most common upper respiratory tract infection, affecting an estimated 16% of the US adult population. In Europe, acute sinusitis affects an estimated 2 % and chronic rhino-sinusitis 10 % of the adult population.

Sinusitis can be :

  • Acute, which is usually caused by a bacterial infection in the sinuses that results from an upper respiratory tract infection.
  • Sub-acute or chronic, which refers to long-term swelling and inflammation of the sinuses that may be caused by bacteria (such as Staphylococcus aureus) or fungus and may involve allergy, environmental factors (pollution…).
The different sinusitis
AcuteSymptoms last for up to 4 weeks
Sub-acuteSymptoms last for 4-12 weeks
ChronicSymptoms last for 3 months or longer
Paranasal sinuses
Main pathogens involved in Rhino-sinusitis
BacteriaStreptococcus pneumoniae (30-35%), Haemophilus influenzae (20-25 %), Moraxella catarrhalis (20%), Staphylococcus aureus
VirusesRhinovirus, Influenza A et B, Parainfluenza, Coronavirus (which are the primary pathogens), Respiratory Syncytial Virus, Adenovirus and Enterovirus
FungiAspergillus, Alternaria, Bipolaris and Curvularia species

The most common pathogens responsible for Rhino-sinusitis